Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Immunoprecipitation: 2 μg, Western Blot: 1:200-1:1000
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Description
N-cadherin Monoclonal Antibody (13A9). N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. N-cadherin's function is dependent on its association with the actin-cytoskeleton and is mediated through interactions between the C-terminal region of N-cadherin and the cytoplasmic catenin proteins. The stability of this association is regulated by phosphorylation and dephosphorylation of beta-catenin. Further, N-cadherin is a calcium dependent cell-cell adhesion glycoprotein comprised of five e
Immunogen
n/a
Other Names
Cadherin-2, CDw325, CD325 Neural cadherin, Calcium-Dependent Adhesion Protein