A broad spectrum kinase inhibitor used in proteomics; inhibits FAK, Flt3, JAK2, JAK3, Src, Aurora kinase A, and VEGF receptor 3 (IC50s = 4, 1, 3, 28, 2, 18, and 3 nM, respectively); binds to kinases from every major group and captures all members of the AKT family of proteins; captured 235 kinases from MDA-MB-231 breast cancer cells using large-scale kinome profiling