Nrp1, Recombinant, Rat, aa22-855, His-Tag (Neurophilin-1)
Description
Purity ~90% (SDS-PAGE). Nrp1, also known as neuropilin-1, is a transmembrane glycoprotein that regulates axon guidance and angiogenesis. It acts as a receptor for two different extracellular ligands, class 3 semaphorins and specific isoforms of vascular endothelial growth factor. It is likely to mediate contacts between the dendritic cells and the T lymphocytes via homotypic interactions and is essential for the initiation of the primary immune response. Source: Recombinant protein corresponding to aa22-855 from rat Nrp1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~94.8kD (842aa) 100-150kD (SDS-PAGE under reducing conditions) AA