Nrp1, Recombinant, Mouse, aa22-856, His tag (Neuropilin-1)
Description
Purity ~90% (SDS-PAGE). Nrp1, also known as Neuropilin 1, is a transmembrane glycoprotein that acts as a co-receptor for a number of extracellular ligands including class III/IV semaphorins, certain isoforms of vascular endothelial growth factor and transforming growth factor beta. It binds vascular endothelial growth factor (VEGF)-A and is thought to act as a coreceptor for kinase insert domain-containing receptor (KDR) by associating with KDR and enhancing VEGF signaling. It is a marker of regulatory T cells. Source: Recombinant protein corresponding to aa22-856 from mouse Nrp1, fused to His-Tag at C-terminal, expressed in insect cell. Molecular Weight: ~94.7kD (843aa) 100-150KD (SDS-PAGE under reducing conditions) AA