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Description
Recognizes bovine Synaptophysin. Excellent marker for several neuroendocrine tumors of epithelial origin (pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid) for neuronal and adrenal tumors (pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas). Reacts with transmembrane glycoprotein (Mr 38kD) in synaptic vesicles. Species crossreactivity: human, rat and mouse. Also reacts with rat PC-12 cell line.
Immunogen
Synaptophysin from presynaptic vesicles, prepared from bovine brain.
Other Names
Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38) (BIotin)