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Description
Represents an excellent marker for several neuroendocrine, neuronal and adrenal tumors. Neuronal and adrenal tumors such as pheochromocytomas, paragangliomas, neuroblastomas, ganglioneuroblastomas. Neuroendocrine tumors of epithelial origin: Pancreatic islet cell carcinoma, bronchial and gastrointestinal carcinoids, medullary carcinoma of thyroid. Polypeptide reacting: Mr 38,000 transmembrane glycoprotein of presynaptic vesicles. Reactivities on Cultured Cell Lines (tested so far): Rat PC-12 cell line. Species Crossreactivity: Human, bovine, rat, mouse.
Immunogen
Synaptophysin from presynaptic vesicles, prepared from bovine brain.
Other Names
Synaptophysin (SYP, SYPH, SypI, Major Synaptic Vesicle Protein P38, Syn p38)