Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol.. NRP1, also known as neuropilin-1 isoform a, is a type 1 transmembrane protein. This protein is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor and semaphorin family members. It is a VEGF165 and semaphorin receptor expressed by vascular endothelial cells (EC) and tumor cells. It is a co-receptor for VEGF receptor (VEGFR2) that enhances the binding of VEGF 165 to VEGFR2 and VEGF165-mediated chemotaxis. Also, it plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion. Recombinant human NRP1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size
250ug, 50ug, 10ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Neuropilin-1 isoform a, NRP1, BDCA4, CD304, NP1, NRP, VEGF165R