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Description
Mouse Anti-MANF (AA 116-185) Recombinant Antibody (CBFYM-1368). This product is mouse antibody that recognizes MANF. The antibody CBFYM-1368 can be used for immunoassay techniques such as: ELISA, IF, WB. The protein encoded by this gene is localized in the endoplasmic reticulum and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later
Immunogen
Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: DSQICELKYD KQIDLSTVDL KKLRVKELKK ILDDWGETCK GCAEKSDYIR KINELMPKYA PKAASARTDL
Other Names
Mesencephalic Astrocyte Derived Neurotrophic Factor; Mesencephalic Astrocyte-Derived Neurotrophic Factor; Arginine-Rich, Mutated In Early Stage Tumors; ARMET; ARP; Arginine-Rich Protein; Protein ARMET