Recombinant Rat Vascular endothelial growth factor A (Vegfa)
Description
Purity > 90% as determined by SDS-PAGE. MW: 26.1kDa. Full Length of Mature Protein: 27-214aa. N-terminal 6xHis-tagged. Rattus norvegicus (Rat). Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis.