Purity ~95% (SDS-PAGE). HRSP12, also called ribonuclease uK114, is an endoribonuclease found predominantly in human adult kidney and liver, and which is responsible for inhibiting translation by cleaving mRNA. This protein cleaves phosphodiester bonds only in single-stranded RNA. It may be an important biomarker for heptatic carcinoma. Source: Recombinant protein corresponding to aa1-137 of human HRSP12, fused to His-tag at N- terminal expressed in E. coli. Molecular Weight: ~16.6kD AA