Purity ~90% (SDS-PAGE). Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. Source: Recombinant protein corresponding to aa20-300 from human HSD17B11, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~46.8kD AA
Size
10ug, 50ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
17-beta-hydroxysteroid dehydrogenase 11, 17-beta-HSD 11, 17bHSD11, 17betaHSD1117-beta-hydroxysteroid dehydrogenase XI, 17-beta-HSD XI ,17 beta HSDXI Cutaneous T-cell lymphoma-associated antigen HD-CL-03, CTCL-associated antigen HD-CL-03 Dehydrogenase/reductase SDR family member 8 Retinal short-chain dehydrogenase/reductase 2, retSDR2 Short chain dehydrogenase/reductase family 16C member 2