4-Methyl Estradiol 3-O-Benzoate is an intermediate in the synthesis of 4-Methyl-17α-Estradiol which is a related compound of 17 α-Estradiol (E887995), a biologically active estrogen in human breast cancer cells in tissue culture. 17-εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer's disease and ischemic stroke. Molecular Formula: C26H30O3 Solubility: Dichloromethane, Methanol Molecular Weight: 390.51