A potent and selective inhibitor of Kv7.2 channels (IC50 = 69 nM); more potent than the (R)-enantiomer and racemic mixture (IC50s = 944 and 160 nM, respectively); selective for Kv7.2 over other Kv channel subtypes, G protein-coupled receptors, transporters, calcium channels, and KATP and hERG potassium channels; inhibits the MT1 receptor 61% when used at a concentration of 10 μM ,