Purity ~98% (SDS-PAGE). Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4kD protein containing 71aa residues, including the four highly conserved cysteine residues present in CC chemokines. Source: Recombinant protein corresponding to 71aa residues from human Eotaxin-3, expressed in E. coli. Molecular Weight: ~8.4kD Biological Activity: Determined by its ability to chemoattract human CCR3/HEK 293 cells using a concentration range of 1-2ug/ml. Endotoxin: <0.1ng/ug of protein (<1EU/ug) AA Sequence: TRGSDISKTC CFQYSHKPLP WTWVRSYEFT SNSCSQRAVI FTTKRGKKVC THPRKKWVQK YISLLKTPKQ L