Purity ~85% (SDS-PAGE). Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. Source: Recombinant protein corresponding to aa2-147 from human AIF1, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~32.6kD AA