Highly Purified (~98%). Synonyms: 1DE 1, Inducer of Definitive Endoderm 1 Chemical Name: 1-[2-[(2-carboxyphenyl)methylene]hydrazide]-heptanedioic acid Molecular Formula: C15 H18 N2O5 Molecular Weight: 306.3 CAS Number: 1160927-48-9 Purity: ≥98% Applications: FA Appearance: Crystalline solid Description: IDE1 activates the TGF-beta signaling pathway and induces definitive endoderm formation in human and mouse embryonic stem cells. It is also reported to increase the levels of Nodal expression, induce Smad2 phosphorylation and SOX17 expression. Storage: Soluble in organic solvents such as ethanol and DMSO. DMSO up to 80mM.