eIF3 is the largest translation factor and consists of 12 subunits. Complex organization of eIF3 explains its role in almost all steps of translation initiation, including ribosomal subunit anti-association activity, ternary complex recruitment to the 40S subunit, 43S pre-initiation complex loading onto mRNA, and ribosomal scanning. MW: 650 kDa. Purity ≥99%