BAIAP2, Recombinant, Human, aa1-522, His-Tag (BAI1-associated protein 2)
Description
Purity ~90% (SDS-PAGE). BAI1-associated protein 2, also known as BAIAP2, is a ubiquitous regulator of the actin cytoskeleton. It mediates filopodia formation under the control of Rho-family GTPases. BAIAP2 is expressed in the cytoplasm and links small membrane-bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It has also been identified as interacting with the dentatorubral- pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Source: Recombinant protein corresponding to aa1-522 of human BAIAP2, fused to His-tag at C-terminal expressed in E. coli. Molecular Weight: ~58.4kD AA