Intercellular adhesion molecule 1 (ICAM-1), also known as CD54, binds the leukocyte integrins LFA-1 and Mac-1. ICAM-1 expression is weak on leukocytes, epithelial and resting endothelial cells, as well as some other cell types, but expression can be stimulated by IFN-gamma, TNF-alpha, IL-1 beta and LPS. Soluble ICAM-1 is found in a biologically active form in serum, probably as a result of proteolytic cleavage from the cell surface. Sample Type: Cell culture supernatants, serum, plasma, and tissue Intended Use: The Human sICAM-1 BioAssay? ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative detection of Human sICAM-1 concentrations in cell culture supernatants, serum, plasma, and tissue. Sensitivity: 60pg/ml Range: 125-8000pg/ml Specificity: Recognizes human sICAM-1. Sample Volume: 100ul/well Test Principle: This assay employs the Sandwich immunoassay technique. An anti-h sICAM-1 monoclonal coating antibody is adsorbed onto microwells. sICAM-1 present in the sample or
Size
48 tests
Concentration
n/a
Applications
ELISA
Other Names
sICAM-1 BioAssay? ELISA Kit (Human) (Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1)