Recombinant Mouse Bone morphogenetic protein 8B (Bmp8b)
Description
Purity > 90% as determined by SDS-PAGE. MW: 28.7kDa. Full Length of Mature Protein: 261-399aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. Involved in the generation of primordial germ cells; this function involves Bmp4 in a synergistic manner though separate receptor complexes seem to be involved. Required for the initiation and maintenance of spermatogenesis. Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.