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Description
Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor. This LILRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-81 amino acids from the Central region of human LILRA2.
Immunogen
Human LILRA2.
Other Names
ILT1; LIR7; CD85H; LIR-7; Leukocyte immunoglobulin-like receptor subfamily A member 2; Leukocyte immunoglobulin-like receptor 7; Immunoglobulin-like transcript 1; ILT-1; CD85 antigen-like family member H; CD85h antigen; LILRA2; leukocyte immunoglobulin-like receptor; subfamily A (with TM domain); member 2