Purity ~85% (SDS-PAGE). Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30aa. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. Source: Recombinant protein corresponding to aa52-750 from human Neprilysin, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~81.83kD AA