A flavonoid from C. ordata with anticancer and antiplasmodial activity; inhibits the viability of HL-60, U937, MOLT-3, Raji, K562, MCF-7, SK-MEL-1, and A549 human tumor cell lines with IC50 values ranging from 5.5-24.1 μM; induces G2-M arrest and inhibits tubulin polymerization in vitro; inhibits breast cancer resistance protein (BCRP/ABCG2; IC50 = 0.040 μM in a vesicular transport assay); reduces in vitro proliferation of chloroquine-resistant P. falciparum (IC50 = 4.8 μM),