Purity ~95% (SDS-PAGE). CCL19 is a chemokine that belongs to the CC family of growth factors and signals through the CCR7 receptor. CCl19 has been shown to be expressed in the thymus, lymph nodes and in activated bone marrow stromal cells. When anti-inflammatory signals are released, expression of CCL19 gets down-regulated - specifically by IL-10. Source: Recombinant protein corresponding to human MIP-3 Beta expressed in E. coli. Molecular Weight: ~9.1kD Biological Activity: Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL). The ED50 for this effect is typically 0.10.3ug/ml. Endotoxin: <1EU/ug (LAL)