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Description
Caveolin-1 (Tyr14) Polyclonal Antibody. ? Target Background: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Caveolin-1 around the phosphorylation site of Tyr14 [HL(p-Y)TV]