Glial cell-derived neurotrophic factor, also known as GDNF is a small protein that potently promotes the survival morphologicaldifferentiation of various neuronal which is encoded by the GDNF gene. Furthermore, it may also modulate local neuronal effectsin distal regions of the motor neuron. In addition, GDNF is a founding member of the GDNF family of ligands (GFL) and hasbeen shown to interact with GFRA2 and GDNF family receptor alpha 1. Recombinant rat GDNF (monomer) contains 135 aminoacids residues, which is a disulfide-linked homodimer and it shares 99 % and 93 % a.a. sequence identity with mouse and humanGDNF. MW: 15.2 kDa. Purity > 95 % by SDS-PAGE and HPLC analyses
Size
2 ug, 10 ug, 1 mg, 100 ug, 250 ug, 500 ug
Concentration
Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, 500 mM NaCl, pH 6.4
Applications
HPLC, SDS-PAGE
Other Names
Rat Glial Cell-derived Neurotrophic Factor protein