Purity >95% by SDS-PAGE, MW: 30.1 kDa. Glial Derived Neurotrophic Factor comes as a dimer having a 135/270 amino acid chain. Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.