Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1000
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Description
NBPF8 Polyclonal Antibody. This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart diseas
Immunogen
n/a
Other Names
Putative neuroblastoma breakpoint family member 8, NBPF8, NBPF8P