Granulocyte Colony Stimulating Factor, Recombinant, Human, Western Blot Positive Control
Description
Highly Purified (~95%) . GCSF (CSF3), is a glycoprotein that is produced and secreted by macrophages stimulated with endotoxin. It is also produced by a number of different tissues to stimulate the bone marrow to produce granulocytes and stem cells. G-CSF then stimulates the bone marrow to pulse them out of the marrow into the blood. It also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils. The natural human GCSF exists in two forms, a 174- and 180-amino-acid-long protein (precursor 204aa, mature peptide 175aa; chromosome 17q11.2-q12, ~19.6kD). The more-abundant and more-active 174aa form has been used in the development of pharmaceutical products (Available under the names Neupogen or Granulokine (Amgen/Roche) and Granocyte (Rhone-Poulenc). GCSF is used to treat neutropenia (a disorder characterized by an extremely low number of neutrophils in blood). The PEG (polyethylene glycol) form has a much longer half-life, r
Size
100ul
Concentration
n/a
Applications
WB
Other Names
Granulocyte Colony Stimulating Factor, Recombinant, Human, Western Blot Positive Control (G-CSF, GCSF, C17orf33, Colony Stimulating Factor 3 (Granulocyte), CSF3, CSF3OS, Filgrastim, Lenograstim, MGC45931, Pluripoietin)