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Description
DUSP12 Monoclonal Antibody (PK15-AF28F3). The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene produc
Immunogen
n/a
Other Names
DUSP1; YVH1; YVH1 protein-tyrosine phosphatase ortholog; dual specificity protein phosphatase 12; dual specificity tyrosine phosphatase YVH1; serine/threonine specific protein phosphatase