Recombinant Mouse Immunoglobulin superfamily member 2 (Cd101), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 31.2kDa. Partial: 22-266aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Glu-Trp-Ile EWI motif-containing protein 101 (EWI-101) (CD_antigen: CD101) (Igsf2)