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Description
Rabbit IgG polyclonal Picoband? antibody for AH receptor-interacting protein(AIP) detection. Tested with WB in Human. No cross reactivity with other proteins. AIP, also known as, ARA9 or XAP-2, is a protein that in humans is encoded by the AIP gene. This gene is mapped to 11q13.2. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. AIP may play a positive role in aryl hydrocarbon receptor-mediated signalling possibly by influencing its receptivity for ligand and/or its nuclear targeting. It has been shown that AIP is the cellular negative regulator of the hepatitis B virus (HBV) X protein. AIP mutations may be the cause of a familial form of acromegaly, familial isolated pituitary adenoma (FIPA).
Immunogen
E.coli-derived human ARA9 recombinant protein (Position: D91-H330). Human ARA9 shares 95% amino acid (aa) sequence identity with both mouse and rat ARA9.
Other Names
AH receptor-interacting protein;AIP;Aryl-hydrocarbon receptor-interacting protein;HBV X-associated protein 2;XAP-2;Immunophilin homolog ARA9;AIP;XAP2;