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Description
Mouse Anti-LRP5 Recombinant Antibody (CBYCL-469). Provided herein is a Mouse monoclonal antibody against LRP5. The antibody can be used for immunoassay techniques, such as WB. LRP5 is a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.