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Description
Rat Anti-Lrp5 Recombinant Antibody (CBYJL-2408). Provided herein is a Rat monoclonal antibody, which binds to Low Density Lipoprotein Receptor-Related Protein 5 (Lrp5). The antibody can be used for immunoassay techniques, such as FC. Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a essential role in bone formation. Plays a role in norrin (NDP) signal transduction. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signal
Immunogen
n/a
Other Names
HBM; LR3; LRP7; OPPG; BMND1; mKIAA4142; low-density lipoprotein receptor-related protein 5; LRP-5; LRP-7; low-density lipoprotein receptor-related protein 7