Immunocytochemistry: 1:50-1:200, Immunofluorescence: 1:50-1:200, Western Blot: 1:500-1:2000
Reviews / Ratings
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Description
DRD5 Polyclonal Antibody. D5DR (dopamine receptor D5, DR1B, DRD1L2) is a G protein-coupled receptor of the D1-like family that stimulates adenylyl cyclase and has a 10-fold higher affinity for dopamine than the D1 subtype. D5DR is present in neurons in the limbic regions of the brain. D5DR mRNA is most abundant in discrete cortical areas (layers II, IV and VI), the dentate gyrus and hippocampal subfields with low levels in the striatum. There are five major types of dopamine receptors. All are G protein-coupled metabotropic receptors, and can be excitatory or inhibitory to the post-synaptic neuron. D1 (D1A, D1C, D1D) and D5 (D1B) receptors belong to the D1-like receptor family. The D2, D3 and D4 receptors belong to the D2-like receptor fami