A sesquiterpene with diverse biological activities; lethal to A. subpictus, A. albopictus, and C. tritaeniorhynchus mosquito larvae (LC50s = 6.19, 7.39, and 12.05 mg/ml, respectively); reduces growth of MCF-7 breast cancer cells by ~50% at 32 mg/ml; reduces viability of Caco-2 cells (IC50 = 24.4 mg/ml); reduces histamine-induced paw edema in mice as well as carrageenan-induced TNF-α and IL-1β production and paw edema in mice and rats at 50 mg/kg; reduces carrageenan-induced production of PGE2 and expression of iNOS and COX-2 in rats