KEY FEATURES & APPLICATIONS: ? Water-soluble ? Adds a 5-atom spacer arm (8.1 A?) to minimize steric hindrance ? The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc. ? Commonly used to convert primary amines into sulfhydryl groups in a one-step process is called thiolation ? Amine reactive at pH 7-10 and is also an effective thiolation reagent for polysaccharides ? Useful RNA-protein crosslinking reagent. MW: 137.63. Purity ≥90% by NMR