Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. In addition, EGFR signaling has also been shown to play a role in carcinogenesis. This kit is based on sandwich enzyme-linked immune-sorbent assay technology. The density of color is proportional to the Human EGFR amount of sample captured in plate.
Size
100 assays
Concentration
n/a
Applications
This ELISA kit is used for quantitative measurement of EGFR in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.