A cell-permeable inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively); inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC50s = 2.3-2.5 μM)
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
179246-75-4 biochemical inhibitor kinase protein cancer signal transduction receptor biochemistry inhibit 4-[[4-[benzyloxy]phenyl]amino]-6,7-dimethoxyquinazoline 4557W epidermal growth factor 2 tyrosine EGFR c-ErbB2 cErbB2 ErbB-2 HER2 HER-2 Neu