Epithelial Splicing Regulatory Protein 2 (ESRP2) (C-Term)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse
Isotype
n/a
Format
purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
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Description
Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Synonyms: Polyclonal Esrp2 antibody, Anti-Esrp2 antibody, epithelial splicing regulatory protein 2 antibody, 9530027K23Rik antibody, Rbm35b antibody.
Immunogen
Esrp2 antibody was raised in rabbit using the C terminal of Esrp2 as the immunogen