Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1) peptide
Description
NFKB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a complex of protein subunits that ultimately control transcription of cellular reponse to stressful stimuli, such as: cytokine exposure, free radicals, UV and irradiation, bacterial and viral secretions, etc. NF-kB also assists in regulating the immune response to infection. When mis-regulated, NF-kB has been implicated in cancer, inflammation, autoimmune disorders, and insufficient clearing of viral infections.Synonyms: DNA binding factor KBF1; DNA-binding factor KBF1; NF-kappabeta; nuclear factor NF-kappa-B p105 subunit; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B DNA binding subunit; NF-kB; NF-KB