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Description
BMPR2 Polyclonal Antibody, Alexa Fluor? 647 Conjugated. ? Target Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Immunogen
KLH conjugated synthetic peptide derived from human BMPR2. Immunogen Range: 940-990/1038
Other Names
BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II; Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR2