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Description
This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. This IRGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-179 amino acids from the C-terminal region of human IRGM.
Immunogen
Human IRGM.
Other Names
Immunity-related GTPase family M protein 1; Interferon-inducible protein 1; LPS-stimulated RAW 264.7 macrophage protein 47 homolog; LRG-47; IRGM; IFI1; IRGM1; LRG47; Immunity-related GTPase family M protein