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| Antigenic Specificity | Neurofilament, Light Polypeptide (NEFL) |
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| Clone | 1H3 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
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| Immunogen | Purified recombinant fragment of human NEFL expressed in E. coli. |
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| Other Names | NEFL|nefl|zgc:136626|AI847934|CMT2E|NF-L|NF68|Nfl|CMT1F|NFL|XNF-L |
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| Gene, Accession # | Gene ID: 4747 |
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| Catalog # | ABIN969548 |
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| Price | |
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| Order / More Info | Neurofilament, Light Polypeptide (NEFL) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 19123978, 19158810 |
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