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Description
MC4 Receptor Antibody. MC4R (Melanocortin-4 receptor) belongs to the GPCR superfamily that is responsible for multiple signal transduction pathway which includes the cAMP and MAPK signaling pathways. Expression of MC4R has been reported in brain. From genetic studies of mice and humans, it was established that MC4 receptor plays a critical role in appetite regulation. Mutation in the MC4R gene is associated with obesity in humans.
Immunogen
Synthetic peptide surrounding amino acid 301 of mouse MC4 Receptor