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Description
Recombinant Mouse Anti-MUC1 Antibody scFv Fragment (6A6). Mucins are extensively O-glycosylated proteins that are predominantly expressed by epithelial cells. The secreted and membrane-bound mucins form a physical barrier that protects the apical borders of epithelial cells from damage induced by toxins, microorganisms and other forms of stress that occur at the interface with the external environment. The transmembrane mucin 1 (MUCl) can also signal to the interior of the cell through its cytoplasmic domain. MUCl has no sequence similarity with other membrane-bound mucins, except for the presence of a sea urchin sperm protein-enterokinase-agrin (SEA) domainELISA, Neutralization