BRD3 bromodomain (1-416 aa) (His-Tag), human recombinant
Description
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as ``readers'' of histone acetylation marks regulating the transcription of target promoters. The BET family of proteins, defined by tandem Bromodomains and an Extra Terminal domain, include BRD2, BRD3, BRD4, and BRDT. The BET proteins p
Size
100 μg
Concentration
0.5 mg/ml
Applications
RUO
Other Names
ORFX, RING3L, Bromodomain containing protein 3, RING3-like protein