MW: 14.4 (140 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher). Purity >95% by SDS-PAGE. alpha-Synuclein E46K is a mutant form of alpha-synuclein which is changed at position 46 from glutamate (E) to lysine (K). Recent studies have shown that this mutant (E46K) of alpha-synuclein causes Parkinson and Lewy Body dementia (DLB). alpha-Synuclein E46K was overexpressed in E. coli and purified to apparent homogeneity by using conventional column chromatography techniques
Size
0.1 mg, 0.5 mg
Concentration
1 mg/ml (determined by BCA assay)
Applications
SDS-PAGE
Other Names
[SNCA; NACP; PARK1; alpha-Synuclein; alpha synuclein E46k; alpha-synuclein e46k; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; Alpha synuclein; Alpha-synuclein isoform NACP140; alphaSYN; MGC105443; MGC110988; MGC127560; MGC64356; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid; precursor of PARK 1; PARK 4; PARK4; Parkinson disease familial 1; PD 1; PD1; Synuclein alpha,]