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Description
ETS variant 5,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,expressed in brain,placenta and other tissues involved in development. Tissue specificity: Ubiquitous. ERM is expressed in Sertoli cells and spermatogonial stem cells (SSCs). Studies on knockout mice have shown that it is required for SSC self-renewal but not differentiation, thus affected mice exhibit progressive germ cell depletion.
Immunogen
Purified recombinant fragment of human ETV5 expressed in E. Coli.
Other Names
ERM; ETV5; ETS translocation variant 5; Ets-related protein ERM